Medications That May Affect Your Hearing

Medications are a crucial aspect of healthcare, with millions of prescriptions filled annually in the United States alone. While they play a vital role in preventing, treating, and managing various health conditions, it’s essential to be aware of potential side effects, especially when it comes to your hearing. In this article, we’ll explore four classes of medications that could be lurking in your medicine cabinet, potentially causing hearing loss or tinnitus.

NSAIDs (Non-Steroidal Anti-Inflammatory Drugs):
NSAIDs, or non-steroidal anti-inflammatory drugs, are commonly used for pain relief and to reduce inflammation. These medications, including well-known brands like ibuprofen and aspirin, may impact your hearing.

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Research suggests that NSAIDs can reduce blood flow to the cochlea, the hearing organ, affecting its function. While short-term use at recommended dosages is generally considered safe, prolonged or high-dose usage can lead to hearing loss or an increase in tinnitus perception. It is crucial to adhere to recommended dosages and consult with your healthcare provider about the long-term use of NSAIDs.

Loop Diuretics:
Loop diuretics, such as furosemide, are prescribed to individuals with heart or kidney conditions to reduce fluid buildup in the body. These medications intentionally alter the ratios of sodium, calcium, and potassium, affecting fluid retention not only in the body but also in the cochlea. This can result in temporary hearing loss or tinnitus. Like NSAIDs, prolonged or high-dose use of loop diuretics may lead to permanent hearing damage. If you are prescribed loop diuretics, it’s essential to discuss potential side effects, including their impact on hearing, with your healthcare provider.

Aminoglycoside Antibiotics:
Aminoglycoside antibiotics, broad-spectrum bacterial antibiotics like gentamycin, are utilized to treat various infections. These antibiotics are believed to create free radicals, oxygen molecules that can cause damage to the cochlea structures. Depending on the dosage, temporary or permanent hearing loss may occur days to weeks after antibiotic administration. High doses can even lead to sudden sensorineural hearing loss, requiring immediate medical attention. If you are prescribed aminoglycoside antibiotics, it’s crucial to discuss potential hearing-related side effects with your healthcare provider to ensure proper monitoring and early intervention if necessary.

Chemotherapy drugs, such as cisplatin, are indispensable in the treatment of cancers and bone marrow conditions. While the precise mechanism behind their impact on hearing is complex, studies indicate that chemotherapy can result in hearing loss or tinnitus. For more than half of those undergoing chemotherapy, the hearing loss often occurs in the high pitches and is generally permanent. Hearing loss itself can contribute to or exacerbate tinnitus. Audiological evaluations before and after chemotherapy are crucial to monitor the impact on the auditory system. If you are experiencing hearing difficulties or concerns about tinnitus during or after chemotherapy, scheduling a comprehensive hearing evaluation with audiology experts is recommended.

Signs of hearing loss can vary depending on the severity, but here are some common signs to look out for:

  • Difficulty understanding speech: Struggling to follow conversations, especially in noisy environments.
  • Frequently asking others to repeat themselves: Needing people to repeat what they’ve said, particularly in quiet or noisy settings.
  • Turning up the volume: Frequently turning up the volume on the television, radio, or electronic devices to a level that others find too loud.
  • Avoidance of social situations: Withdrawing from social gatherings or avoiding situations where hearing might be challenging.
  • Misinterpreting speech or sounds: Mishearing or misunderstanding words or phrases, leading to confusion or frustration.
  • Ringing or buzzing in the ears (tinnitus): Experiencing persistent ringing, buzzing, or other noises in the ears, which may accompany hearing loss.
  • Difficulty hearing high-pitched sounds: Difficulty hearing sounds like birds chirping, doorbells, or the ringing of a phone.
  • Muffled or distorted sounds: Sounds may seem muffled, distorted, or unclear, making it challenging to understand speech or enjoy music.
  • Difficulty hearing consonants: Struggling to distinguish between similar-sounding consonants, such as ‘s’ and ‘th’ or ‘f’ and ‘v.’
  • Fatigue or stress: Feeling exhausted or stressed from the effort of trying to hear and understand conversations or sounds.


It is essential to understand that not everyone will experience side effects from these medications. However, being aware of the potential risks and discussing them with your healthcare provider is crucial. Audiological evaluations, conducted by professionals in the field, play a significant role in monitoring the impact of medications on your hearing. If you are prescribed any of the mentioned medications and notice changes in your hearing or tinnitus perception, seeking prompt evaluation and discussing alternative treatments with your healthcare provider is imperative. Hearing health is a critical aspect of overall well-being, and staying informed is the first step toward preserving it.



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